Blood Cancer UK: strategic call for innovative, large-scale clinical trials
Overview
Remit
This scheme is open to applications for innovative, large-scale clinical trials testing multiple interventions that are adaptable in design (for example, multi-arm, multi-stage trials).
Applications must focus on the testing and development of at least one of the following:
- Novel treatments or treatment combinations;
- Improvements in treatment sequencing/scheduling;
- More personalised treatment approaches, for instance through use of/development of predictive or prognostic biomarkers.
All applications must also:
- Be inclusive by design and have an inclusive recruitment strategy in place to ensure patients recruited are representative of the disease group/subgroups under investigation.
- Have a clearly defined pathway to impact, aiming to achieve paradigm-shifting changes to current clinical practice or disease management for people living with the least survivable blood cancers.
Studies must be focused on patients with blood cancer who, with current clinical management, have a predicted 5-year survival of less than 50% at the point of diagnosis.
Grants will typically range from £4m to £8m, for up to seven years. The maximum that can be requested is £8
Applications for smaller-scale clinical trials in any type of blood cancer or precursor condition should be submitted to their annual Transformational Research Awards scheme.